Produktdaten Intended use Product informations

Adiponectin high sensitive ELISA (TECO®)

Produktdaten

Total Human Adiponectin

Sample preparation

Blood collection - fasting is recommended.
Samples are stable for maximum 2 days at room temperature. Long-term storage stable for maximum 2 years at -20 °C.
Max. 5 freeze and thaw cycles.

Reference values

	mg/l
Men Adult	8-10
Female Adult	10-12
cut-off	10

Comprehensive clinical reference data related to age and gender are available for this test.

Product name	Adiponectin high sensitive ELISA (TECO®)
Cat-Nr.	TE1013
Range	1 – 100 ng/ml native Adiponectin
Sensitivity	< 0.6 ng/ml
Incubation time	2 hours
Sample volume	5 µl (dilute >1:300 serum and plasma). For other biological fluids see protocol.
Sample type	Serum, heparin plasma, breast milk, urine, saliva, CSF, cell culture
Species	Human
Tests	96
Method	ELISA
Adiponectin is mainly synthesized by adipocytes, but also in muscle cells and hepatocytes. Until now, IGF-I is the only known natural inductor of the synthesis. Adiponectin correlates with BMI and is associated with the Insulin-Resistance and therefor linked with Type II Diabetes. Adiponectin is also associated with glucose- und lipometabolism. Furthermore Adiponectin is involved in inflammatory processes and is of importance for the appearance of arteriosclerosis and coronaritis. Our Total Human Adiponectin ELISA is suited for the determination of Adiponectin in human plasma and serum.

Intended use

Adiponectin is a 30kDa protein and its percentage in serum proteins is 0.01%. In vivo, it appears with different oligomers and it is mainly synthesized by adipocytes. Until now, IGF-1 is the only known natural inductor of synthesis.
Low Adiponectin levels are closely associated with insulin resistence and metabolic syndrome as well as an increased risk of type 2 diabetes mellitus and cardiovascular disease.
Today, Adiponectin is thought to act as an endogenic insulin sensitizer by decreasing excessive glucose levels without increasing insulin concentrations and by stimulating the burning of adipose tissue in muscle and liver.
Adiponectin is associated with glucose and lipid metabolism and is assumed to have direct antiatherogenic characteristics. Furthermore, it is involved in inflammatory processes.

Clinical significance:
• Obesity
• Atherosclerosis
• Energy metabolism
• Coronary artery disease
• Metabolic syndrome
• Polycystic ovary syndrome (PCOS)

Product informations

Adiponectin high sensitive ELISA (TECO®) - Product Specifications (PDF 473.2 KB)

Back to overview