Produktdaten Intended use Product informations

Sclerostin TECO® High sensitive

Produktdaten

Regulation of Bone Turnover.

Sample preparation

Samples should be collected without hemolysis. Allow the blood to clot, separate serum by centrifugation and test samples within 2 hours. Serum is stable for 3 days at room temperature, 5 days at 2 – 8 °C, 2 years at -20 °C. Longer storage at -80°C. Maximum 3 freeze- and thaw cycles.

Reference values

Sclerostin Values are dependent on age and gender.

Subjects	Mean (ng/ml)	SD (ng/ml)	Mean (pmol/l)	SD (pmol/l)	N
Pre-menopausal female	0.48	0.14	21.12	6.16	20
Post-menopausal female	0.58	0.17	25.52	7.48	19
Men	0.64	0.15	38.16	6.6	10

Clinically Healthy Subjects

Product name	Sclerostin TECO® High sensitive
Cat-Nr.	TE1023-HS
Range	0.05 – 3 ng/ml
Sensitivity	LOD: 0.009 ng/ml LLOQ: 0.058 ng/ml LOQ: 3.5 ng/ml
Incubation time	4.5 hours
Sample volume	25 µl
Sample type	Plasma, Serum, Cell culture
Species	Human
Tests	96
Method	ELISA
Sclerostin is the protein product of the SOST gene and inhibits bone formation by regulating osteoblast function and promoting osteoblast apoptosis. Reduced expression of sclerostin can result in van Buchem disease, while a complete absence of Sclerostin results in Sclerosteosis. Our Human Sclerostin High Sensitivity (HS)ELISA is designed for the measurement of Sclerostin in human serum, plasma and cell culture (osteocytes and chondrocytes).

Intended use

Sclerosteosis
Van Buchem disease
Osteoporosis
Chronic Kidney Disease
Cardiac Research
Others

Sclerostin TECO® High sensitive

Produktdaten

Intended use

Product informations

Sclerostin TECO® High sensitive - Instruction for Use (PDF 821.5 KB)

Sclerostin TECO® High sensitive - Product Specifications (PDF 350.7 KB)

Sclerostin TECO® High sensitive - Techn. & clin. Bulletin (PDF 1.6 MB)