Osteocalcin (1-43/49) N-MID human
Produktdaten
Sample preparation
Separate serum or plasma within 3 hours after blood collection. Specimens may be stored at 2-8°C for 6 days. For longer storage keep at -20°C. Max. 3 freeze and thaw cycles. Avoid hemolysis.
Reference values
| Range (ng/ml) | Mean (ng/ml) | |
| Healthy adults (n=40) | 3.8 – 25.3 | 11.7 (median 11.4 ng/ml; SD 3.8 ng/ml) |
| 95 percentile cut-off: 17 ng/ml | ||
| Premenopausal | 5.4 - 15.2 | 10.3 |
| Postmenopausal | 3.9 - 21.6 | 13.8 |
| Men | 5.4 - 15.1 | 10.8 |
| Endstage renal disease patients (n=39) | 21 - 119 | 60.6 (median 59.6 ng/ml; SD 26.2 ng/ml) |
| Product name | Osteocalcin (1-43/49) N-MID human |
| Cat-Nr. | KT-809 |
| Range | 4 - 64 ng/ml |
| Sensitivity | 0.3 ng/ml |
| Incubation time | 1.5 hours |
| Sample volume | 25 μl |
| Sample type | serum, plasma |
| Species | Human |
| Tests | 96 Tests |
| Method | ELISA |
Intended use
Osteocalcin can be helpful as a biochemical marker for bone turnover. Increased concentrations are found in patients with different bone diseases that are marked by increased osteoblast activity.
- Paget’s disease
- Osteomalacia
- Bone fibrosis
- Renal osteodystrophy
- Follow up of osteoporosis treatment
Increased osteocalcin levels were found in patients with elevated levels of thyroid hormones, growth hormones, vitamin D and parathyroid hormones.