Bone metabolism

Product name

Osteocalcin (1-43/49) N-MID human

Range4 - 64 ng/ml
Sensitivity0.3 ng/ml
Incubation time1.5 hours
Sample volume25 μl
Sample type

serum, plasma

Sample preparation

Separate serum or plasma within 3 hours after blood collection.
Specimens may be stored at 2-8°C for 6 days. For longer storage
keep at -20°C. Max. 3 freeze and thaw cycles. Avoid hemolysis.

Reference values
  Range (ng/ml) Mean (ng/ml)
Healthy adults
3.8 – 25.3 11.7 (median 11.4 ng/ml;
                SD 3.8 ng/ml)
95 percentile cut-off: 17 ng/ml
Premenopausal 5.4 - 15.2 10.3
Postmenopausal 3.9 - 21.6 13.8
Men 5.4 - 15.1 10.8
Endstage renal disease
patients (n=39)
21 - 119 60.6 (median 59.6 ng/ml;
               SD 26.2 ng/ml)




Tests96 Tests
Intended use

Osteocalcin can be helpful as a biochemical marker for bone turnover. Increased concentrations are found in patients with different bone diseases that are marked by increased osteoblast activity.

• Paget’s disease
• Osteomalacia
• Bone fibrosis
• Renal osteodystrophy
• Follow up of osteoporosis treatment

Increased osteocalcin levels were found in patients with elevated levels of thyroid hormones, growth hormones, vitamin D and parathyroid hormones.

Product informations

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