NTX-Serum
Produktdaten
N-terminal Telopeptide of Collagen Type-I
Sample preparation
Specimen should be collected at the same time of the day. Store samples refrigerated at 2-8°C for up to 24 hours or frozen at -20 °C for longer storage. Stable up to 3 freeze and thaw cycles.
Reference values
nmol Bone Collagen Equivalents per litre = nM BCE
| Mean | SD | Range (mean ± 2 SD) | |
| Premenopausal women (25 - 49 years) | 12.6 | 3.2 | 6.2 - 19.0 |
| Postmenopausal women | 12.9 - 22.7 | ||
| Men (31 - 80 years) | 14.8 | 4.7 | 5.4 - 24.2 |
Reference values from children are available.
| Product name | NTX-Serum |
| Cat-Nr. | NTx9021 |
| Range | 5 - 40 nM BCE |
| Sensitivity | 3.2 nM BCE |
| Incubation time | 2 hours |
| Sample volume | 50 µl (dilute 1:5) |
| Sample type | Serum, cell culture |
| Species | Human, bovine, sheep, porcine, rabbit, rat, rhesus macaque |
| Tests | 96 Tests |
| Method | ELISA |
Intended use
NTX-Serumtest is used for the quantitative management of cross-linked N-telopeptides of type I collagen in human serum. The NTX molecule is bone specific due to the unique amino acid sequences of the cross-linked alpha-2 (I) N- telopeptide. Release of the NTX molecule is mediated by osteoclasts. Elevated levels of NTX indicate elevated bone resorption.
NTX levels are used for:
- monitoring of antiresorptive therapy in osteoporosis
- Paget’s disease
- monitoring and early detection of bone metastasis.