Liver

Product name	Collagen IV, Human serum Novel Liver Injury Biomarkers
Cat-Nr.	TE1053
Range	15.6 – 1000 μg/l
Sensitivity	15.6 μg/l
Incubation time	1 hour
Sample volume	50 μl
Sample type	Serum
Sample preparation	Samples can be stored at 2 – 8 °C for one week Samples may be stored at -20 °C for 12 months. Repeated freeze-thawing of samples should be avoided.
Reference values	99 ± 23 μg/l (Mean ±1 SD, N= 180)
Species	Human
Cross reaction	Cross reactivity is less than 2 % with Collagen II and less than 0.5 % with other forms of collagen.
Tests	96
Method	ELISA
Note	Interference: No significant interference has been observed in this assay with lipaemic, haemolytic or icteric samples. Lipaemia: Less than 10 % interference up to 1200 Formazine turbidity units. Haemolysis: Less than 10 % interference up to 3 g/l haemoglobin. Icteris: Less than 10 % interference up to 0.2 g/l bilirubin.
Intended use	Chronic liver disease comprises a number of progressive disorders which culminate in liver cirrhosis and which are characterized by excessive deposition of collagen. Collagen IV deposition increases in the liver with the progression of fibrosis and this increase is directly correlated in rising serum levels. Serum Collagen IV levels have been demonstrated to be an effective marker of disease progression and also therapeutic efficacy in several disorders such as hepatitis C patients and abstaining alcoholics.
Product informations	Kit Instructions (PDF 207,8 kB) Technical Bulletin (PDF 2,5 MB) Cross-reaction all species (PDF 70,3 kB)

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Liver

Collagen IV, Human serum