Liver
| Product name | α-GST, Human serum & plasmaNovel Liver Injury Biomarkers |
| Cat-Nr. | BIO91 |
| Range | 2.5 - 80 μg/l |
| Sensitivity | 1.9 μg/l |
| Incubation time | 2 hours |
| Sample volume | 100 μl (Suggested initial dilution 1:5) |
| Sample type | Serum & Plasma |
| Sample preparation | Centrifuge within 3 hours from time of collection and transfer the sample from the original tube for storage. Samples can be stored at 20 – 25 °C for up to 48 hours, at 2 – 8 °C for up to one week or at -20 °C for >1 year. Repeated freeze thawing of samples should be avoided. |
| Reference values | 0 - 12 μg/l |
| Species | Human |
| Cross reaction | No cross-reactivity was observed with μGST at 500 μg/l or π-GST at 500 μg/l |
| Tests | 96 |
| Method | ELISA |
| Note | Serum & Plasma: α-GST is expressed in hepatocytes and its increase in blood is a sensitive indicator of acute hepatic injury. Increased αGST has been demonstrated to be indicative of hepatotoxicity, allograft rejection, viral hepatitis. |
| Intended use | α-GST is a member of the GST superfamily of small cytosolic proteins primarily involved in cellular detoxification reactions. α-GST is approximately 51kDa and can comprise upto 2 % of the cytosolic soluble protein content. As a result of its constitutive nature, α-GST is immediately released into the urine upon lysis of epithelial cells of the proximal tubule. The α-GST EIA provides a method for the quantitative determination of alpha glutathione S-transferase |
| Product informations |
