Hyaluronic Acid - Hyaluronan (HA) ELISA

Produktdaten

Sample preparation

Fasting blood collection. Serum or EDTA Plasma stable for 72 hours at 2-8 °C, 6 months at -20°C, longer storage at -80°C. Maximum 3 freeze- and thaw cycles.

Reference values

Hyaluronic Acid Values are dependent on age and gender and influenced by food intake and physical activity.

Clinically Healthy Subjects n=53 between 16 and 79 years.
36.7 ± 23.5 ng/ml.

  Mean (ng/ml) SD (ng/ml)
Female premenopausal 20,1 14,3
Female postmenopausal 50,3 19,9
Male 42,6 24,6

 Cutoff 90 ng/ml ± 2 SD

Product name Hyaluronic Acid - Hyaluronan (HA) ELISA
Cat-Nr. TE1017-2
Range 15 – 1000 ng/mL (Pharmacopeia Standard)
LOD: . 2.7 ng/ml
LLOQ: 15 ng/ml
ULOQ: 1000 ng/ml
Sensitivity 10 ng/ml
Incubation time 3 hours
Sample volume 100 µl
Sample type

Serum, EDTA-plasma and cell culture supernatant

Species

Human

Tests 96 Tests
Method ELISA

Hyaluronic acid (HA), also known as hyaluronan or hyaluronate is synthesized by fibroblasts and other specialized connective tissue cells and is a major component of connective tissues and thus distributed ubiquitously in the organism. HA can act as a biomarker for joint diseases and correlates in RA and OA patients with the degree of joint inflammation, synovial proliferation and the degree of joint space narrowing. Due to the decreased capacity for hyaluronan clearance, HA is an important biomarker for most chronic liver diseases which are characterised by fibrosis and cirrhosis. Our Hyaluronic Acid PLUS ELISA is suited for the determination of hyaluronic acid in plasma, serum and other biological fluids.


Intended use

  • Diagnosis and monitoring of liver fibrosis and cirrhosis
  • Diagnosis and monitoring of joint diseases
  • HA is also important in diabetes, as a tumor marker and in pulmonary infections.

Product informations