Cartilage metabolism

Product name


Collagen synthesis
C-terminal Propeptide of Collagen Type-II (PIICP)

Range50 - 2000 ng/ml
Incubation time4 hours
Sample volume25 μl (dilute 1:2)
Sample type

Serum (also used for cell culture, synovial fluid, cartilage extract)

Sample preparation

Serum samples should be aliquoted, rapidly frozen and stored at -70 °C. Avoid repeated freezing/thawing of samples.
Serum: stable > 1 year at -70 °C.


Human (also used for horse, bovine, dog, mouse, rat, rhesus macaque, sheep, guinea pig). The use of rabbit samples may lead to high background interference.

Tests96 Tests
Intended use

CP-II as a biomarker is used in the investigation of the cartilage synthesis in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and cartilage injury and repair in human as well as some animal models. The CP-II-concentration in cartilage correlates directly with the synthesis of the type-II collagen.

Product informations

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