Growth metabolism

Product name

IGF-I Mouse / Rat

mouse-and rat-Insulin like Growth Factor - I

Cat-Nr.E25
Range0.5 – 18 ng/ml
Sensitivity0.029 ng/ml
Incubation time2 hours RT
Sample volume50 µl (after dilution 1:100)
Sample type

Serum, plasma (Heparin, EDTA, Citrate)

Sample preparation

Samples are stable at room temperature for 2 days. Long-term storage should be carried out at –20°C or below. Maximum 5 freeze/thaw cycles.

Species

mouse, rat

Tests96 Tests
MethodELISA
Intended use

Beside different cell culture models and studies with human patients, mice and rats are suitable model organisms for basic research and pre-clinical studies.

Insulin-like growth factors (IGF) I and II play a pivotal role in regulating the proliferation and differentiation of many cell types. IGF-I is identical with Somatomedin C and has a molecular weight of 7649 daltons.

Its major regulators are growth hormone and nutrition. In contrast to many other peptide hormones, IGFs are avidly bound to specific binding proteins (IGFBP). The seven IGFBPs which are known at present either bind IGF-I and IGF-II with similar affinities or show a preference for IGF-II.

Product informations

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