Cartilage metabolism

Product name

CS-846

Chondroitin Sulfate 846 Epitope of Proteoglycan Aggrecan

Cat-Nr.60-1004
Range20-1000 ng/mL
Incubation time3 hours
Sample volume10 μl (dilute 1:5)
Sample type

Serum (also used for synovial fluid, cell culture, cartilage extract)

Sample preparation

Serum samples should be aliquoted, rapidly frozen and stored at -70 °C. Avoid repeated freezing/thawing of samples.
Serum: stable > 1 year at -70 °C.

Species

Human (also used for horse, bovine, dog, rabbit, guinea pig, rat, rhesus macaque, sheep). The use of mouse samples may lead to high background interference.

Cross reaction

Chondroitin sulfate, dermatan sulphate and keratan sulfate alone, either in their native or degraded state, show no reactivity.

Tests96 Tests
MethodELISA
Intended use

CS-846, a chondroitin sulfate epitope, which is normally only present on intact aggrecan “fetal-like” proteoglycan, is used as a biomarker in the investigation of the cartilage synthesis/turnover in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and cartilage injury and repair in human as well as some animal models.

Product informations

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