Bone metabolism

Product name

Osteopontin, Human

Cat-Nr.TE 5000
Range5 - 320 ng/ml / 76.9 – 4920 pmol/l
Sensitivity3.33 ng/ml / 51.2 pmol/l
Incubation time2 hours
Sample volume100 µl (dilute plasma 1:5 – 1:10; dilute urine > 1:200)
Sample type

Urine, EDTA plasma, cell culture

Sample preparation

Specimen should be measured immediately after collection or stored frozen. Avoid repeated freeze/thaw cycles. Before use, thaw samples at low temperature and mix them thoroughly.

Species

Human (Rat and Mouse kits are available)

Tests96 Tests
MethodELISA
Intended use

Osteopontin is a highly acidic calcium-binding glycosylated phosphoprotein secreted by many cell types
The determination of Osteopontin can be helpful for the investigation of:

  • early hepatocellular carcinoma - OPN is significantly up-regulated and considered as a promising novel marker
  • pathogenesis of alcoholic liver disease, considered as new relevant biomarker for significant liver fibrosis
  • diabetic nephropathy
  • osteoporosis
  • bone metabolism
  • development of bone metastases
  • chronically-inflammatory diseases

 

 

Product informations

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