Bone metabolism

Product name

Osteocalcin Intact, Human (Quidel®)

Cat-Nr.8002
Range2 - 32 ng/ml
Sensitivity0.45 ng/ml
Incubation time3.5 hours
Sample volume25 µl
Sample type

EDTA Plasma, Serum, cell culture

Sample preparation

Keep samples refrigerated at 2-8°C immediately after collection and during preparation. Specimens should be prepared and tested within  2 hours after collection or should be stored frozen at -20°C.

Reference values
  ng/ml
Women and men (>25 years) 3.7 - 10.0
 Premenopausal women (<=40) 1.15 - 9.3
Postmenopausal women (>=60) 2.98 - 13.8
Men 4.2 - 11.3
Species

Human, rabbit, porcine, sheep, goat, bovine, horse, cynomolgus macaque, guinea pig (1:10 – 1:20 diluted)

Cross reaction

No cross-reaction with human osteocalcin fragments

Tests96 Tests
MethodELISA
Intended use

Osteocalcin can be helpful as a biochemical marker for bone turnover. Increased concentrations are found in patients with different bone diseases that are marked by increased osteoblast activity:

  • Paget’s Disease
  • Osteomalacia Bone fibrosis
  • Renal Osteodystrophy
  • Follow up of Osteoporosis treatment

Increased osteocalcin levels were found in patients with elevated levels of thyroid hormones, growth hormones,  vitamin D and parathyroid hormones.

Product informations

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