Bone metabolism

Product name

DPD (Quidel®)

Desoxypyridinolin-Crosslinks

Free DPD is measured

Cat-Nr.8007
Range3 - 300 nmol/l
Sensitivity1.1 nmol/l
Incubation time3 hours
Sample volume50 µl (dilute 1:10)
Sample type

Urine, cell culture

Sample preparation

Use preservative-free first or second morning urine. Collect specimens before 10 a.m. Store samples refrigerated at 2-8°C for a maximum of 7 days or frozen at -20°C. Protect specimens from exposure to light.

Reference values
  Range
(nmol/mmol Cr)
Average
(nmol/mmol Cr)
Premenopausal women
(25 - 44 years)
3.0 - 7.4 5.0
men (25 - 55 years)  2.3 - 5.4 3.8


Reference values from children are available.

Species

Human, rat, mouse, rabbit, guinea pig, dog, porcine, sheep, cynomolgus macaque, bovine, horse, squirrel, baboon, rhesus macaque

Cross reaction

Negligible cross-reaction with DPD peptides and peptide bound pyridinoline.

Tests96 Tests
MethodELISA
Intended use

Quidel® DPD provides a quantitative measurement of the excretion of deoxypyridinoline (DPD) crosslinks as an indicator of bone resorption. Elevated levels of urinary DPD indicate elevated bone resorption in individuals. Measurement of DPD is intended as an aid for monitoring bone resorptional changes in postmenopausal women receiving hormonal or bisphosphonate anti resorptive therapies and in individuals diagnosed with osteoporosis.

Product informations

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