Bone metabolism

Product name

BAP MicroVue™ Quidel®

Bone-specific Alkaline Phosphatase, Enzyme activity of bound BAP is measured

Cat-Nr.8012
Range2-140 U/l (1-70 µg/l)
Sensitivity0.7 U/l
Incubation time3.5 hours
Sample volume20 µl
Sample type

Heparinized plasma, serum, cell culture

Sample preparation

Plasma samples should not be treated with EDTA or citrate because of the inhibition of the BAP enzyme. Keep samples refrigerated at 2-8°C for storage of less than 5 days. For long-term storage freeze specimens at -20°C or below.

Reference values
  U/L
Female (25 - 44 years Premenopausal) 11.6 - 29.6
Female (≥ 45 years Postmenopausal) 14.2 - 42.7
Male (> 25 years) 15.0 - 41.3

Reference values from children are available. 

Species

Human, rabbit, porcine, dog, cat, sheep, goat, bovine, horse, baboon, rhesus macaque, cynomolgus macaque

Cross reaction

Minimal cross-reactivity to liver (3 – 8%), intestinal (0.4%) and placental (0%) alkaline phosphatases.

Tests96 Tests
MethodELISA
Intended use

BAP (bone specific alkaline phosphatase) is a highly specific marker of osteoblast activity during bone remodeling. Measurement of BAP is intended for use as an aid in:

  • management of postmenopausal osteoporosis and Paget’s disease.
  • monitoring postmenopausal women on hormonal or bisphosphonate therapy.
  • predicting skeletal response to hormonal therapy in postmenopausal women.
  • diagnostic analysis metastasis.

See also reference: Clinical & Technical Monograph: Bone specific alkaline phosphatase (BAP).

Product informations

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