Paramètres spéciaux

Nom du produit	HAMA
	Human Anti-Mouse IgG Antibody
Cat. no	KT-805
Gamme	50 – 1500 ng/ml
Sensibilité	2 ng/ml
Durée d'incubation	2 hours
Volume échantillon	25 μl
Echantillon	Serum, plasma
Précautions	Serum, plasma should be separated within 3 hours after blood collection. Stable for 72 hours at 2–8°C, for longer storage keep at - 20°C. Max. 3 freeze and thaw cycles.
Valeurs de référence	n=170 Cut-off 25 ng/ml
Espèces	Human
Nombre de Tests	96 Tests
Méthode	ELISA
Informations utiles	- Literature: Complement Diagnostics (pdf-File 1,850 kb) - Kit Instructions (pdf-File 169 kb) - Cross-reaction all species (pdf-File 71 kb)
Application	Clinically, mouse monoclonal antibodies (IgG) and their fragments are used for in-vivo diagnostic procedures (radionuclides) and as treatment for patients with various diseases. In patients, even a single dose injection of murine monoclonal IgG may induce immune response directed against this foreign protein (immunogen). In the circulation, human antibody against murine IgG could bind to the injected murine IgG and, therefore, diminish the efficacy of either the application of the in-vivo diagnosis or treatment. Especially, the HAMA would increase the risk of anaphylactic complications to subsequent administration of the murine IgG based therapy.