Paramètres spéciaux

Nom du produit	HAHA
	Human Anti-human IgG Antibody
Cat. no	KT-806
Gamme	1 – 27 μg/ml
Sensibilité	1 μg/ml
Durée d'incubation	2 hours
Volume échantillon	25 μl
Echantillon	Serum, plasma
Précautions	Serum, plasma should be separated within 3 hours after blood collection. Stable for 72 hours at 2 – 8°C, for longer storage keep at -20°C. Max. 3 freeze and thaw cycles.
Valeurs de référence	n=86 Cut off 0.5 μg/ml
Espèces	Human
Nombre de Tests	96 Tests
Méthode	ELISA
Informations utiles	- Literature: Complement Diagnostics (pdf-File 1,850 kb) - Kit Instructions (pdf-File 141 kb) - Cross-reaction all species (pdf-File 71 kb)
Application	Clinically, humanized monoclonal antibodies (IgG) and their fragments are used for in-vivo diagnostic procedures (radionuclides) and treatment for patients with various diseases. In patients, even a single dose injection of a humanized monoclonal antibody or its fragment may induce immune response directed against this foreign protein (immunogen). Also, people with autoimmune diseases, such as rheumatoid arthritis, lupus, etc. produce autoantibodies against human IgG. In the circulation, human antibody against human IgG could bind to the injected human IgG and, therefore, diminish the efficacy of either the application of the in-vivo diagnosis or treatment. Especially, the HAHA would increase the risk of an anaphylactic complication to subsequent administration of the humanized monoclonal antibody based therapy.