Oxidative Stress & Cardiovascular Disease

Productname	MDA-oxLDL
	Malondialdehyde oxidised low densitiy lipoprotein
Cat-No.	BI-20022
Range	0 – 10 µg/ml
Sensitivity	0.3 µg/ml
Incubation time	3.5 h
Sample volume	20 µl
Sample type	Serum, plasma (Citrate, EDTA or Heparin)
Sample preparation	Centrifuge freshly collected blood as soon as possible. Aliquoted samples should be stored at -20°C or lower. Maximum 4 freeze-thaw-cycles.
Species	Human
Tests	96
Method	ELISA
Product informations	- Kit Instructions (pdf-File 311 kb) - Information: The Oxidative Stress&Atherosclerosis Product Line (pdf-File 1752 kb)
Intended use	Oxidatively modified lipoproteins (ox-LDLs) play an important role in the progression of atherosclerosis and coronary artery disease. Low-density lipoprotein (LDL), the main carrier of plasma cholesterol, consists of a hydrophobic core and a surface monolayer of polar lipids and Apolipoprotein-B (ApoB). Oxidative stress and the consequent formation of free radicals lead to the peroxidation of ApoB. Malondialdehyde (MDA) has been identifiedas one of the major lipid peroxidation products of LDL, thus playing an important role in the LDL oxidation. The MDA ox-LDL ELISA specifically detects MDA-modified Apo B in human serum and plasma.