Monoklonale Antikörper

A murine monoclonal antibody to a neo-epitope expressed on iC3b

Specifications:
Isotype: IgG2bk
Protein Concentration: > 1.0 mg/ml
Volume/Vial: 100 µl
Storage: 2-8°C

Specificity:
This monoclonal antibody was raised against purified human iC3b.
It is specific for a neo-antigen on iC3b.

Applications:
Quidel's iC3b monoclonal antibody has been used in a variety of experimental techniques including EIA, Western Blot, Flow Cytometry, RIA, Hemagglutination and Immunohistochemistry.

References:

• Tamerius, J.D., M. Pangburn, et al., Detection of a neoantigen on human iC3b and C3d by monoclonal Antibody, J. Immunol. 135:2015.(1985).
• Rogers, J., N. Cooper, et al., Complement Activation by ß-amyloid in Alzheimer disease, PNAS 89:10016-10020, (1992).
• Gemmell, C, A flow cytometric immunoassay to quantify adsorption of complement activation products on artificial surfaces, J Biomed Mater Res 37, 474-480, (1997).
• S. Merri, Junnikala, S., Exceptional Resistance of Human H2 Gioblastoma Cells to Complement Mediated Killing by Expression and Utilization of Factor H and Factor H Like Protein 1, J Immunol 164:11 6075-6081, (2000).
• R. Marks, Hindmarsh, E., Complement activation occurs on subendothelial extracellular matrix in vitro and is initiated by retraction or removal of overlying endothelial cells, J Immunol 160:6128-6136, (1998).