Monoclonal Antidodies

A murine monoclonal antibody to an epitope in the C3d domain of C3

Specifications:
Isotype: IgG1k
Protein Concentration: > 1.0 mg/ml
Volume/Vial: 100 µl
Storage: 2-8°C

Specificity:
This monoclonal antibody was raised against purified human C3.
It is specific for an antigen expressed on the C3d domain of C3 and is reactive to all C3d-containing fragments of C3, but not with C3 itself.
Applications:
Quidel's C3 (C3d) monoclonal antibody has been used in a variety of experimental techniques including EIA and Immunohistochemistry.

References:

• Tamerius, J.D., M. Pangburn, et al., Detection of a neoAntigen on human iC3b and C3d by monoclonal Antibody, J. Immunol. 135:2015 (1985).
• Tamerius, J.D., M.k. Pangburn, et al., Selective inhibition of functional sites of cell bound C3b by hybridoma derived antibodies, J. Immunol 128:512, (1982).
• Rogers, J., N. Cooper, et al., Complement Activation by ß-amyloid in Alzheimer disease. PNAS 89:10016-10020 (1992).