Growth metabolism

Productname	IGF-I Mouse / Rat
	mouse-and rat-Insulin like Growth Factor - I
Cat-No.	E25
Range	0.5 – 18 ng/ml
Sensitivity	0.029 ng/ml
Incubation time	2 hours RT
Sample volume	50 µl (after dilution 1:100)
Sample type	Serum, plasma (Heparin, EDTA, Citrate)
Sample preparation	Samples are stable at room temperature for 2 days. Long-term storage should be carried out at –20°C or below. Maximum 5 freeze/thaw cycles.
Species	mouse, rat
Tests	96 Tests
Method	ELISA
Product informations	- Kit Instructions (pdf-File 574 kb) - Cross-reaction all species (pdf-File 71 kb)
Intended use	Beside different cell culture models and studies with human patients, mice and rats are suitable model organisms for basic research and pre-clinical studies. Insulin-like growth factors (IGF) I and II play a pivotal role in regulating the proliferation and differentiation of many cell types. IGF-I is identical with Somatomedin C and has a molecular weight of 7649 daltons. Its major regulators are growth hormone and nutrition. In contrast to many other peptide hormones, IGFs are avidly bound to specific binding proteins (IGFBP). The seven IGFBPs which are known at present either bind IGF-I and IGF-II with similar affinities or show a preference for IGF-II.