| Productname |
 C1-Inhibitor MicroVue™ Quidel® |
|
Functional C1 Inhibitor Proteins |
| Cat-No. |
A003 |
| Range |
Concentrations of Functional C1-INH are expressed as Mean Percentage. Range 35 - 100 %. |
| Incubation time |
2 hours |
| Sample volume |
10 µl (dilute 1:101) |
| Sample type |
Serum and EDTA plasma |
| Sample preparation |
Specimens should be collected aseptically and prepared. EDTA plasma sample may be held at room temperature (15-30 ºC) for up to 24 hours. Serum sample should not be stored at room temperature for longer than
6 hours. If exceeded, the plasma or serum must be stored frozen (-20 ºC or below). Avoid freezing and thawing of the sample. |
| Reference values |
Concentrations ≥ 68 % Mean Normal is considered normal. |
| Species |
Human |
| Specificity |
C1-INH-Reactant, binds specific to functional active C1-INH. |
| Tests |
96 Tests |
| Method |
ELISA |
| Product informations |
- Literature: Complement Diagnostics (pdf-File 1,850 kb)
- Kit Instructions (pdf-File 194 kb)
- Cross-reaction all species (pdf-File 71 kb)
|
| Intended use |
The C1-Inhibitor assay measures the amount of functional C1 inhibitor protein (C1-INH) in human plasma or serum. This protease inhibitor has enzyme regulating functions. A deficiency of functionally active C1-INH may lead to life-threatening angioedema. Two major forms of C1-INH deficiency have been reported: the congenital form, termed hereditary angioedema (HAE), and the acquired form, which is associated with a variety of diseases including lymphoid malignancies. Hereditary angioedema is characterized by transient but recurrent attacks of nonpruritic swelling of various tissues throughout the body. |
| Keywords product |
C1-INH, ELISA, C1 Inhibitorproteins, Heriditary angiooedema, Complement pathway, Complement cascade |
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