Cartilage metabolism Product details

Productname	CP II / PIICP
	Collagen synthesis. C-terminal Propeptide of Collagen Type-II (PIICP)
Cat-No.	60-1003
Range	50-2000 ng/ml
Incubation time	4 hours
Sample volume	25 μl per replicate, triplicates recommended
Sample type	Serum (also used for cell culture, synovial fluid, cartilage extract)
Sample preparation	Serum samples should be aliquoted, rapidly frozen and stored at -70 °C. Avoid repeated freezing/thawing of samples. Serum: stable > 1 year at -70 °C.
Species	Human (also used for horse, bovine, dog, mouse, rat, rhesus macaque, sheep, guinea pig). The use of rabbit samples may lead to high background interference.
Tests	96 Tests
Method	ELISA
Product informations	- Kit Instructions (pdf-File 67 kb) - Cross-reaction all species (pdf-File 71 kb) - Bone & Cartilage Metabolism (pdf-File 2480 kb) - Cartilage Monograph (pdf-File 512 kb) - Information: RA Biomarkers (pdf-File 329 kb) - Information: OA Biomarkers (pdf-File 235 kb)
Intended use	CP-II as a biomarker is used in the investigation of the cartilage synthesis in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and cartilage injury and repair in human as well as some animal models. The CP-II-concentration in cartilage correlates directly with the synthesis of the type-II collagen.
Keywords product	CP II, ELISA, Cartilage Synthesis, Type II Collagen-Synthesis, Rheumatoid Arthritis, Osteoarthritis, Cartilagemarker, Therapy efficiency