Bone metabolism Product details
| Productname |
 Osteocalcin Intact, Human (Quidel®) |
| Cat-No. |
8002 |
| Range |
2 - 32 ng/ml |
| Sensitivity |
0.45 ng/ml |
| Incubation time |
3.5 hours |
| Sample volume |
25 µl |
| Sample type |
EDTA Plasma, Serum, cell culture |
| Sample preparation |
Keep samples refrigerated at 2-8°C immediately after collection and during preparation. Specimens should be prepared and tested within 2 hours after collection or should be stored frozen at -20°C. |
| Reference values |
| |
ng/ml |
| Women and men (>25 years) |
3.7 - 10.0 |
| Premenopausal women (<=40) |
1.15 - 9.3 |
| Postmenopausal women (>=60) |
2.98 - 13.8 |
| Men |
4.2 - 11.3 |
|
| Species |
Human, rabbit, porcine, sheep, goat, bovine, horse, cynomolgus macaque, guinea pig (1:10 – 1:20 diluted) |
| Cross reaction |
No cross-reaction with human osteocalcin fragments |
| Tests |
96 Tests |
| Method |
ELISA |
| Product informations |
- Kit Instructions (pdf-File 173 kb)
- Animal reference Values (pdf-File 25 kb)
- Cross-reaction all species (pdf-File 71 kb)
- Cell culture (pdf-File 93 kb)
- Datasheet (pdf-File 129 kb)
- Bone & Cartilage Metabolism (pdf-File 2,480 kb)
|
| Intended use |
Osteocalcin can be helpful as a biochemical marker for bone turnover. Increased concentrations are found in patients with different bone diseases that are marked by increased osteoblast activity:
- Paget’s Disease
- Osteomalacia Bone fibrosis
- Renal Osteodystrophy
- Follow up of Osteoporosis treatment
Increased osteocalcin levels were found in patients with elevated levels of thyroid hormones, growth hormones, vitamin D and parathyroid hormones. |
| Keywords product |
Osteocalcin intact, ELISA, Bone turnover, Bone formation, Bone matrix, Bone remodeling, Osteocalcin intact, Osteomalacia, Paget's disease, Bone fibrosis, Renal Osteodystrophia, Bone marker, Therapy efficiency |
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