Bone metabolism Product details

Productname Osteocalcin (1-43/49) N-MID human

Cat-No. KT-809

Range 4 - 64 ng/ml

Sensitivity 0.3 ng/ml

Incubation time 1.5 hours

Sample volume 25 μl

Sample type

serum, plasma

Sample preparation

Separate serum or plasma within 3 hours after blood collection.
Specimens may be stored at 2-8°C for 6 days. For longer storage
keep at -20°C. Max. 3 freeze and thaw cycles. Avoid hemolysis.

Reference values

	Range (ng/ml)	Mean (ng/ml)
Healthy adults (n=40)	3.8 – 25.3	11.7 (median 11.4 ng/ml; SD 3.8 ng/ml)
95 percentile cut-off: 17 ng/ml
Premenopausal	5.4 - 15.2	10.3
Postmenopausal	3.9 - 21.6	13.8
Men	5.4 - 15.1	10.8
Endstage renal disease patients (n=39)	21 - 119	60.6 (median 59.6 ng/ml; SD 26.2 ng/ml)

Species

Human

Tests 96 Tests

Method ELISA

Product informations - Cross-reaction all species (pdf-File 71 kb)
- Bone & Cartilage Metabolism (pdf-File 2480 kb)

Intended use

Osteocalcin can be helpful as a biochemical marker for bone turnover. Increased concentrations are found in patients with different bone diseases that are marked by increased osteoblast activity.

• Paget’s disease
• Osteomalacia
• Bone fibrosis
• Renal osteodystrophy
• Follow up of osteoporosis treatment

Increased osteocalcin levels were found in patients with elevated levels of thyroid hormones, growth hormones, vitamin D and parathyroid hormones.

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